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Dysport vs. Botox: what's the difference?

Botox (onabotulinumtoxinA) and Dysport (abobotulinumtoxinA) are both botulinum toxins and effectively have the same action on muscle function. In our San Francisco Bay Area practice we frequently use both products interchangeably. Some patients prefer or respond to one more favorably than the other so our recommendation is to try both and formulate your own opinion. One of the biggest differences between then two products is that for every one unit of Botox approximately 2.5 units of Dysport are required to achieve the same results. Because of this, many offices, including our own, price per treatment area regardless of the units required. Alternatively, Dysport may be priced lower per unit than Botox, however prices will vary from practice to practice.

Clinical Context

The choice between Dysport and Botox mostly comes down to spread and dosing, not raw effectiveness. Dysport's smaller formulation tends to diffuse a bit more once injected, which some providers favor for larger areas like the forehead, while Botox's slightly more contained pattern can suit smaller, precise sites. Both are botulinum toxin type A and block the same nerve signals to muscles. Your injector's experience with dosing units for each brand often matters more than which one you pick.

Answered by Dr. Steven Williams, President Emeritus of ASPS

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