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How Long Does Restylane Last?

The amount of time that Restylane lasts can vary depending upon the area that it is injected. Restylane injected in the lips seems to last the shortest amount of time - anywhere from 3-6 months. Injections around the mouth usually last about 6-9 months. Injections under the eyes tend to last longer, about 9-12 months. Follow-up treatments with Restylane in the appropriate timeframe can increase the amount of time needed in between treatments.

Clinical Context

Restylane is a hyaluronic acid gel that has been chemically modified to resist breakdown longer than the hyaluronic acid your body makes naturally. How long it lasts depends on where it's placed: areas with more movement, like the lips, tend to break the gel down faster, while less mobile areas, such as under the eyes, allow it to last longer. Your own metabolism, skin thickness, and the amount of product used also affect how long results hold. Restylane is not permanent and is gradually absorbed by the body over time.

Answered By

Dr. Steven Williams

President Emeritus of ASPS

Dr. Steven Williams is a board-certified plastic and reconstructive surgeon, a diplomate of the American Board of Plastic Surgery, the Past President of the prestigious American Society of Plastic Surgeons, and a charitable person who dedicates his life to those in need of his unique expertise.

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