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Is it safe to get a Botox after a flu shot that contains a very small trace of Neomycin?

Botox is very locally acting so there should not be any problems getting your treatment after the flu vaccine. It works right at the muscle where it's injected and doesn't circulate through the bloodstream the way the trace neomycin from the vaccine does, so the two don't interact. Neomycin sensitivity is something to flag to whoever gives your flu shot, not a concern for Botox itself, since Botox doesn't contain it. If you want to keep things simple, you can space the two appointments a day or two apart, that way if you notice any soreness, redness, or swelling, you'll know which one caused it. If you develop unusual swelling, drooping, or trouble swallowing after treatment, contact my office.

Clinical Context

Botox works locally at the injection site and doesn't interact with vaccine ingredients circulating elsewhere in the body. If you're allergic to neomycin, that's a vaccine consideration, not a Botox one, since Botox doesn't contain it. One practical tip: spacing the two appointments by a day or two can make it easier to tell whether any soreness or swelling came from the shot or the injection.

Answered By

Dr. Steven Williams

President Emeritus of ASPS

Dr. Steven Williams is a board-certified plastic and reconstructive surgeon, a diplomate of the American Board of Plastic Surgery, the Past President of the prestigious American Society of Plastic Surgeons, and a charitable person who dedicates his life to those in need of his unique expertise.

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